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目的:分析酪酸梭菌活菌散辅助治疗新生儿黄疸临床效果。方法:将2016年3月-2017年2月84例新生儿黄疸患儿根据就诊编号随机分两组,分别为常规组42例、活菌组42例。常规组采取常规药物和蓝光照射治疗,活菌组在常规组基础上给予酪酸梭菌活菌散辅助治疗。比较两组黄疸治疗效果;胆红素达到正常水平时间、黄染消退时间、结束治疗时间;干预前后患儿血清胆红素三项指标(直接、间接、总水平)。结果:活菌组黄疸治疗效果高于常规组,P<0.05;活菌组胆红素达到正常水平时间、黄染消退时间、结束治疗时间短于常规组,P<0.05;干预前两组血清胆红素三项指标(直接、间接、总水平)相近,P>0.05;干预后活菌组血清胆红素三项指标(直接、间接、总水平)优于常规组,P<0.05。结论:酪酸梭菌活菌散辅助治疗新生儿黄疸临床效果确切,可缩短疗程,促使血清胆红素恢复正常水平,值得推广和应用。
Objective: To analyze the clinical efficacy of Clostridium butyricum in the treatment of neonatal jaundice. Methods: From March 2016 to February 2017, 84 cases of neonatal jaundice were randomly divided into two groups according to their treatment numbers: 42 cases in the routine group and 42 cases in the viable group. The conventional group was treated with routine drugs and blue light irradiation. The live bacteria group was given adjuvanted Clostridium butyricum in the conventional group. Comparison of two groups of jaundice treatment effect; bilirubin reached the normal level of time, yellow dimming time, ending treatment time; before and after intervention in children with serum bilirubin three indicators (direct, indirect, total level). Results: The viability of jaundice in the viable group was higher than that of the control group (P <0.05). The bilirubin in the viable group reached the normal level, the time of yellow dying and the end of treatment were shorter than those in the conventional group (P <0.05) The three indexes of bilirubin (direct, indirect, total level) were similar (P> 0.05). The three indexes of serum bilirubin (direct, indirect, total level) in the live bacteria group were better than those in the conventional group after intervention (P <0.05). Conclusion: Clostridium butyricum Clostridium adjuvant treatment of neonatal jaundice clinical effect is exact, can shorten the course of treatment, prompting the serum bilirubin return to normal levels, it is worth promoting and application.