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目的观察马来酸桂哌齐特注射液(克林澳)对下肢静脉血栓形成慢性期的临床疗效。方法对60例符合下肢静脉血栓形成慢性期诊断的患者随机分为治疗组及对照组,每组30例,两组患者均接受下床适当活动,活动时穿阶梯压差性弹力袜,抬高患肢、降血脂、华法林5mg口服等常规治疗,治疗组在此基础上加用马来酸桂哌齐特注射液(克林澳)320mg静脉滴注治疗,两组均以14d为1个疗程,比较两组治疗前后血液粘滞度及彩色多普勒血管超声以评价疗效。结果治疗组疗效明显优于对照组,有统计学意义(P<0.05)。结论马来酸桂哌齐特注射液对下肢静脉血栓形成慢性期有较好临床疗效,无明显不良反应。
Objective To observe the clinical efficacy of Cinepazide maleate injection (Kelin O) on chronic venous thrombosis of the lower extremities. Methods Sixty patients with chronic phase of lower extremity venous thrombosis were randomly divided into treatment group and control group, with 30 cases in each group. Both of the two groups were given proper exercise after getting out of bed. Limbs, hypolipidemic, warfarin 5mg oral and other conventional treatment, the treatment group on the basis of plus cinepazide maleate injection (Kelin O) 320mg intravenous infusion of two groups were 14d to 1 A course of treatment, before and after treatment, blood viscosity and color Doppler ultrasound to evaluate the efficacy. Results The treatment group was significantly better than the control group, with statistical significance (P <0.05). Conclusion Cinepazide maleate injection has good clinical curative effect on chronic venous thrombosis of lower extremity with no obvious adverse reaction.