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酚妥拉明(Phentolamin)又名苄胺唑啉(Rigiti-ne),既往用于治疗外周血管挛性疾病和诊断嗜铬细胞瘤等。近10年来对其血液动力学作用有进一步的了解,临床应用日趋广泛。现就国内儿科临床应用情况作一简要介绍。药理作用[1]酚妥拉明系一种短效的α肾上腺素能受体阻滞剂,对α_1、α_2受体均起作用,尤其对后者可使动脉阻抗血管扩张。药效迅速,持续时间短,静注15分钟后作用即消失。能解除血管痉挛及血液瘀
Phentolamin, also known as Rigiti-ne, was previously used to treat peripheral vasculogenic disease and to diagnose pheochromocytoma. In the past 10 years to further understand the role of hemodynamics, clinical application is increasingly widespread. Now on the clinical application of pediatric to make a brief introduction. Pharmacological effects [1] Phentolamine is a short-acting α-adrenergic receptor blockers, α_1, α_2 receptors play a role, especially for the latter can make arterial impedance vasodilation. Efficacy rapid, short duration, the role of intravenous 15 minutes disappear. Can relieve vasospasm and blood stasis