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以唐山市郊区及县区新诊断的101例乳腺癌患者为对象,按性别、年龄、出生地、生活地等因素与相同数量的对照者进行1∶1配比的病例对照研究。在单因素分析中,筛选出绝经年龄迟、行经期长、初产年龄晚、体重大、良性乳腺疾病史及精神刺激为乳腺癌的危险因素。生育次数、总哺乳期、初潮年龄、初潮~初产间隔、初产~末产间隔、口服避孕药、吸烟、饮酒、文化程度、乳腺癌家族史等指标,未发现与乳腺癌有明显联系。将上述因素引入条件Logistic回归模型进行多因素分析,结果与单因素分析一致。
A case-control study with 101 patients with newly diagnosed breast cancer in the suburbs and counties of Tangshan City was conducted, and the same number of control subjects were compared according to sex, age, place of birth, and place of residence. In the univariate analysis, the risk factors for breast cancer were selected as follows: late age of menopause, long menopause period, late first birth, significant body mass, history of benign breast disease, and mental stimulation. The number of births, total lactation period, menarche age, menarche to first birth interval, first birth to final birth interval, oral contraceptives, smoking, alcohol consumption, education level, family history of breast cancer and other indicators did not find any obvious connection with breast cancer. The above factors were introduced into conditional logistic regression model for multivariate analysis. The results were consistent with single factor analysis.