论文部分内容阅读
白细胞介素-2(IL-2)开始是作为 T 细胞生长促进因子被发现,现已知它对包括 T、B 细胞、自然杀伤细胞、单核细胞和少突胶质细胞在内的各种细胞均有生物学作用。新近的研究表明 IL-2受体至少由两种不同的 IL-2结合蛋白组成,即 p~(55)α链(Tac 抗原)和 P~(75)β链。而且 Tac 抗原的另一种可溶性形式( sIL-2R)。在激活的 T 细胞培养上清液已发现。在各种淋巴增生性疾患如成人 T 细胞白血病、毛细胞白血病、B 细胞慢性淋巴细胞白血病和何杰金病患者
Interleukin-2 (IL-2) is initially found as a T cell growth promoting factor and is known to exert its effects on various T cell types including T, B cells, natural killer cells, monocytes and oligodendrocytes Cells have biological effects. Recent studies have shown that the IL-2 receptor consists of at least two different IL-2 binding proteins, namely the p55 chain, the Tac antigen and the P75 chain. But also another soluble form of Tac antigen (sIL-2R). The activated T cell culture supernatant has been found. In various lymphoproliferative disorders such as adult T-cell leukemia, hairy cell leukemia, B-cell chronic lymphocytic leukemia and Hodgkin’s disease