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目的：观察三七总皂甙注射液联用西药治疗肺源性心脏病（肺心病）急性发作期心力衰竭（心衰）的疗效。方法：６０ 例患者随机分为２ 组，每组３０ 例。对照组给予吸氧、抗生素、氨茶碱、利尿剂和地塞米松等治疗；治疗组除以上治疗外加用三七总皂甙注射液６００ ｍ ｇ 加入５％ 葡萄糖或生理盐水中静滴，每日１ 次，２ 组均连续用药１５ 日后评定疗效、心功能和血气分析。结果：治疗组显效率（５６７％ ）、总有效率（９３３％ ）显著高于对照组（分别为３６７％ 和７６７％ ， Ｐ＜ ００１ 和 Ｐ＜ ００５）。治疗组治疗后肺动脉平均压（ Ｐ Ａ Ｍ Ｐ）、肺血管阻力（ Ｐ Ｖ Ｒ）、总外周血管阻力（ Ｔ Ｐ Ｒ）、 Ｐａ Ｏ２ 和动脉血氧饱和度（ Ｓａ Ｏ２）的改善明显优于对照组（ Ｐ＜ ００５ 或 Ｐ＜ ００１）。结论：三七总皂甙注射液与西药合用治疗肺心病急性发作期心衰比单用西药治疗更加有效和安全。
Objective: To observe the effect of panax notoginseng saponin injection combined with western medicine in the treatment of heart failure (heart failure) in acute attack of pulmonary heart disease (pulmonary heart disease). Methods: Sixty patients were randomly divided into two groups, 30 cases in each group. The control group was given oxygen, antibiotics, aminophylline, diuretic and dexamethasone and other treatment; the treatment group in addition to the above treatment plus Panax Saponin injection 600 m g added 5% glucose or saline intravenously daily 1 times, two groups were continuously treated 15 days after the assessment of efficacy, cardiac function and blood gas analysis. Results: The effective rate (567%) and total effective rate (933%) in the treatment group were significantly higher than those in the control group (367% and 767%, P <001 and P≤0 05). The improvement of P A M P, P V R, total peripheral vascular resistance (T P R), Pa O 2 and arterial oxygen saturation (Sa O 2) after treatment in the treatment group was significantly better than Control group (P <005 or P <001). Conclusion: The combination of Panax Notoginseng Saponins injection and western medicine is more effective and safe than the single western medicine in the treatment of acute exacerbation of pulmonary heart disease.