Methylation profile of bovine Oct4 gene coding region in relation to three germ layers

• 作 者: ZHOU Xin-yu LIU Liang-liang JI
• 机 构: CollegeofLifeSciences,SchoolofComputerScience&,Engineering,CollegeofAnimalScienceandTechnology
• 出 处: 农业科学学报：英文版
• 发表日期: 2016年3期
• 关键词: DNA甲基化 基因编码区 中胚层 胎牛 早期胚胎发育 甲基化水平 诱导分化 外显子 bovine DNA methylation octamer-binding
• 基金项目: supported by the Natural Science Foundation of Shaanxi Province, China （2014JQ3104）, the National Natural Science Foundation of China （31000655）, China Postdoctoral Science Foundation funded project （

Previous studies have shown that octamer-binding transcription factor 4(Oct4) plays a significant role in early embryonic development of mammalian animals, and different Oct4 expression levels induce multi-lineage differentiation which are regulated by DN