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本文测定了小儿紫癜肾炎(HSPN)患者血清B因子(BF)、C_3、C_4的含量,试图根据两条途径补体成份含量的变化,探讨HSPN的诊断、治疗和发病机制。 材料和方法 一、对象: (一)正常健康儿童49例,年龄3～15岁,平均年龄7.02±2.46岁。 (二)住院病人80例,年龄3～15岁,平均年龄为6.95±2.09岁。来自黑龙江中医学院附属医院儿科病房,临床诊断为紫癜性肾炎,采集标本时未经任何药物治疗。 二、试剂: (一)抗血清及参考血清: 1.BF由上海第二医科大学附属仁济医院临床检验研究室提供,单扩散效价1:25,批号850421。
The content of serum B factor (BF), C_3 and C_4 in children with purpura nephritis (HSPN) was determined in this paper. The aim of this study is to explore the diagnosis, treatment and pathogenesis of HSPN according to the changes of the content of complement in two pathways. Materials and methods First, the object: (a) 49 cases of normal healthy children, aged 3 to 15 years, with an average age of 7.02 ± 2.46 years. (B) inpatients 80 cases, aged 3 to 15 years old, with an average age of 6.95 ± 2.09 years. From Heilongjiang College of Traditional Chinese Medicine Hospital pediatric ward, clinical diagnosis of purpura nephritis, collecting specimens without any drug treatment. Second, the reagents: (A) of the antiserum and reference serum: 1.BF Renji Hospital Affiliated to Shanghai Second Medical University Clinical Laboratory, single diffusion titer 1:25, lot number 850,421.