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本文报告8例地中海贫血患者经多次输血后,出现了高血压、惊厥、剧烈头痛和脑出血各种并发症,男6例,女2例,年龄13~24岁,既往均无癫痫及高血压史,尿及血液化学检查未发现肾脏疾患。4例行脾切除。每例先后输入3~7单位的血后,常在输血后数日甚至15日出现上述综合征。7例有血压升高,有的高达210/150mmHg,1例未记录;5例有剧烈头痛;7例有癫痛发作,其中6例为全身性发作;4例发生脑出血,其中2例脑脊液为粉红色或血性(内1例脑血管造影正常),2例经尸检证实为脑出血,并可见显微夹层动脉瘤(Microdissecting aneurysm)和高血压脑出血及高血压脑病相似的病理变化;1例脑脊液含有红细胞140/mm~3,提示有小量蛛网膜下腔出
This article reports 8 cases of thalassemia patients after multiple transfusions, there were various complications of hypertension, convulsions, severe headache and cerebral hemorrhage, 6 males and 2 females, aged 13 to 24 years old, no previous epilepsy and high History of blood pressure, urine and blood chemistry check found no kidney disease. 4 cases of splenectomy. Each case has entered 3 to 7 units of blood, often after a few days or even 15 days after the transfusion of the above syndrome. Seven patients had elevated blood pressure, some as high as 210/150 mmHg, one without recording, five with severe headache, seven with epileptic seizures, six with generalized seizures, and four with cerebral hemorrhage, two with cerebrospinal fluid Pink or bloody (1 in normal cerebrovascular angiography), 2 confirmed by autopsy as cerebral hemorrhage, and microtomies aneurysm and hypertensive intracerebral hemorrhage and hypertensive encephalopathy similar pathological changes; 1 Cases of cerebrospinal fluid containing red blood cells 140 / mm ~ 3, suggesting a small amount of subarachnoid out