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目的 研究不稳定型心绞痛患者发作/缓解期血清超敏C -反应蛋白(hs- CRP)水平的动态变化。 方法 对29例不稳定型心绞痛患者发作前后连续监测hs- CRP动态变化,hs- CRP测定方法为增效胶乳散射速率免疫比浊法,同时用化学发光法检测血清肌钙蛋白(cTnI)含量,并与30 例正常对照组进行比较。 结果 不稳定型心绞痛患者发作/缓解期血清hs- CRP均高于正常对照组(P<0 .01),并于发作前2日内出现血清hs- CRP含量升高,发作当日hs- CRP水平达到高峰,与缓解期相比均有高度显著性差别(P<0 .01),hs -CRP与cTnI变化成正相关。 结论 不稳定型心绞痛患者血清hs- CRP的连续监测对预测心绞痛发作具有一定价值。
Objective To study the dynamic changes of serum hs-CRP levels in patients with unstable angina pectoris during onset / remission. Methods 29 patients with unstable angina pectoris before and after the onset of continuous monitoring of hs-CRP dynamic changes, hs-CRP determination method for synergistic latex scattering rate immunoturbidimetry, while using chemiluminescence detection of serum troponin (cTnI) content, And compared with 30 normal control group. Results The serum hs-CRP levels in patients with unstable angina pectoris during onset / remission were significantly higher than those in normal controls (P <0.01). Serum hs-CRP level increased within 2 days prior to the onset of attack. The hs- Peak, compared with the remission were highly significant difference (P <0 .01), hs-CRP and cTnI changes are positively correlated. Conclusion The continuous monitoring of serum hs-CRP in patients with unstable angina pectoris has some value in predicting angina pectoris.