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目的:对冠心病患者动脉粥样硬化性肾动脉狭窄的发病率和危险因素进行探讨。方法:569例冠状动脉造影诊断为冠心病的患者同时进行选择性双侧肾动脉造影。结果:肾动脉狭窄的发生率为16·5%(94/569)。肾动脉狭窄的患病率随着年龄的增加而上升(χ2=19·170,P<0·001)。肾动脉狭窄的发病率随着冠状动脉病变程度的加重而增加(χ2=22·115,P<0·001)。多因素Logistic回归分析中,年龄、高血压和冠心病多支病变为肾动脉狭窄的独立危险因素。结论:对冠心病患者,尤其是多支病变、高血压、高龄的冠心病患者应常规行选择性肾动脉造影。
Objective: To investigate the incidence and risk factors of atherosclerotic renal artery stenosis in patients with coronary heart disease. Methods: 569 patients with coronary artery disease undergoing coronary angiography underwent simultaneous bilateral renal artery angiography. Results: The incidence of renal artery stenosis was 16.5% (94/569). The prevalence of renal artery stenosis increased with age (χ2 = 19 · 170, P <0.001). The incidence of renal artery stenosis increased with the severity of coronary artery disease (χ2 = 22 · 115, P <0.001). Multivariate logistic regression analysis showed that age, hypertension and coronary artery disease were independent risk factors of renal artery stenosis. Conclusion: Coronary heart disease patients, especially multi-vessel disease, hypertension, elderly patients with coronary heart disease should be routine selective renal artery angiography.