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目的:观察克拉霉素颗粒、羟氨苄青霉素、奥美拉唑胶囊三联疗法治疗幽门螺杆菌(Hp)阳性的十二指肠溃疡的疗效。方法:观察组45例口服克拉霉素颗粒、羟氨苄青霉素、奥美拉唑胶囊。对照组45例口服甲硝唑、羟氨苄青霉素、奥美拉唑胶囊,疗程7 d,共治疗2个疗程,疗程结束后4周复查胃镜及Hp。结果:观察组溃疡愈合率及Hp根除率均明显优于对照组。结论:克拉霉素颗粒为主的三联疗法对Hp感染有较高的根除率。
Objective: To observe the efficacy of clarithromycin granules, amoxicillin and omeprazole triple therapy in the treatment of Helicobacter pylori (Hp) -positive duodenal ulcer. Methods: The observation group of 45 cases of oral clarithromycin granules, amoxicillin, omeprazole capsules. Control group, 45 cases of oral metronidazole, amoxicillin, omeprazole capsules, 7 days, a total of 2 courses of treatment, 4 weeks after the end of the course of gastroscopy and Hp review. Results: The ulcer healing rate and Hp eradication rate in the observation group were significantly better than those in the control group. Conclusion: Clarithromycin granules-based triple therapy has a high eradication rate for Hp infection.