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免疫抑制酸性蛋白(Immunosuppresive acidic protein,IAP)是1981年由Tamura等从胃癌患者腹水中分离纯化的一种酸性蛋白。在生理情况下,由肝细胞、巨细胞、粒细胞产生低水平的IAP,其在机体平衡免疫系统中起着负平衡作用。肿瘤患者因机体受肿瘤细胞或其它免疫抑制因子的侵害
Immunosuppressive acidic protein (IAP) is an acidic protein isolated and purified from ascites of gastric cancer patients in 1981 by Tamura et al. Under physiological conditions, low levels of IAP are produced by hepatocytes, giant cells, and granulocytes, which play a negative balance in the body’s balanced immune system. Tumor patients due to the body by tumor cells or other immunosuppressive factors