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脂肪细胞因子可能是过度肥胖和血管功能障碍之间关系的潜在调节因子。该研究在一以社区为基础的较年轻人群中对循环脂肪因子和血管弹性的横断面关系进行评估。方法:研究人员在Framingham第3代队列研究无心血管病的3505例受试者中(平均40岁,53%为女性),研究循环瘦素和瘦素受体浓度、脂联素、视黄醇结合蛋白4、脂肪酸结合蛋白4水平与血管弹
Adipocytokines may be potential regulators of the relationship between obesity and vascular dysfunction. The study evaluated the cross-sectional relationship between circulating adipokines and vascular elasticity in a younger, community-based population. METHODS: The researchers studied the effects of circulating leptin and leptin receptor concentrations, adiponectin, retinol, and leptin on 3505 subjects without cardiovascular disease (mean 40 years, 53% female) in the Framingham Generation 3 cohort, Binding protein 4, fatty acid binding protein 4 levels with vascular bullet