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1糖尿病性高血压[1-3]的界定系肾性高血压的一个类型,糖尿病作为肾脏伤害的病因,糖化血红蛋白在肾小球毛细血管基底膜沉积,致基底膜增厚,导致肾小球硬化症。早在1936年,Kimmelstiel和Wilsou在肾脏病理上发现肾小球呈典型的结节样病变(称κ-w结节),给了糖尿病肾病区别于其它肾脏伤害的准确的概念界定。理论上应不包括糖尿病合并原发性高血压、肾盂肾炎等对肾脏的伤害。
1 The definition of diabetic hypertension [1-3] is a type of renal hypertension, diabetes as a cause of kidney injury, glycated hemoglobin in glomerular capillary basement membrane deposition, resulting in thickening of the basement membrane, leading to glomerular Sclerosis. As early as 1936, Kimmelstiel and Wilsou found that glomeruli were typical nodular lesions (called κ-w nodules) in renal pathology, giving an accurate conceptual definition of diabetic nephropathy as compared to other kidney injuries. In theory, it should not include diabetes with primary hypertension, pyelonephritis and other kidney damage.