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目的:探讨C-反应蛋白(CRP)在急性心肌梗死患者中的变化及与心功能之间的关系。方法:选取121例急性心肌梗死(AMI)患者和50例健康对照者,酶联免疫吸附法(ELISA)检测血清C-反应蛋白(CRP)和B型钠尿肽(BNP)。结果:AMI患者血清CRP显著高于健康对照,AMI伴心功能III,IV级者血清BNP、CRP显著高于AMI伴心功能I,II级者。结论:血清CRP对于急性心肌梗死患者的心功能重要参考指标。
Objective: To investigate the changes of C-reactive protein (CRP) in patients with acute myocardial infarction and its relationship with cardiac function. Methods: 121 patients with acute myocardial infarction (AMI) and 50 healthy controls were enrolled in this study. Serum C-reactive protein (CRP) and B-type natriuretic peptide (BNP) were detected by enzyme linked immunosorbent assay (ELISA). Results: The serum levels of CRP in patients with AMI were significantly higher than those in healthy controls. The serum levels of BNP and CRP in AMI patients with cardiac function III and IV were significantly higher than those with AMI patients with cardiac function I and II. Conclusion: Serum CRP is an important reference index for cardiac function in patients with acute myocardial infarction.