Activation of GABAB receptors alleviates depressive-like behavior induced by chronic cerebral ischem

• 出 处: 中国药理学通报
• 发表日期: 2015年B11期
• 关键词: GABAB RECEPTORS BACLOFEN depressive-like behavior chronic cerebral ISCHEMIA BDNF

Aim To investigate the mechanisms underlying depressive-like behavior induced by chronic cerebral is- chemia in rats. Methods In the present study, a chronic cerebral hypoperfusion model was established by perma- 2VO） in rats. Two weeks after 2VO, GAB- n