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在研究拟肾上腺素药作用时,子宫平滑肌是常用的制备之一。在子宫平滑肌中,研究者们发现许多问题是令人感兴趣的。如卵巢激素可以改变子宫对拟肾上腺素药的反应类型,不同种属的子宫对药物的反应性可有不同,甚至完全相反.为了彻底了解拟肾上腺素药对子宫作用的确切机理,曾进行了大量的研究,现综述如下: 一、β肾上腺素受体 (一)β受体的存在和效应近二十年来,人们对子宫中β受体的存在和效应曾进行过广泛的研究,并已取得较为一致的意见。在不同种属子宫,尤其以大鼠子宫的研究较为深入,Ahlquist很早提出大鼠子宫中存在着β受体,其效应是抑
Uterine smooth muscle is one of the most commonly used preparations for studying the effects of adrenergic drugs. In the uterine smooth muscle, the researchers found that many problems were of interest. Such as ovarian hormones can change the uterine adrenergic drug type of response, different species of uterine reactivity of the drug may be different, or even the opposite.In order to fully understand the exact mechanism of adrenergic drugs on the role of the uterus has been carried out A large number of studies are summarized as follows: 1, β-adrenergic receptor (a) the presence and effect of β receptors in the past two decades, people on the existence and effect of β receptors in the uterus has conducted extensive research and has Obtain a more consistent opinion. In different species of uterus, especially in the study of rat uterus more in-depth, Ahlquist proposed early rat uterus exists β receptor, the effect is