Synthesis, characterization, and biological activities of Pt(Ⅱ) and Pd(Ⅱ2',3',4',5,7-

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Pt(Ⅱ) and Pd(Ⅱ) complexes with 2’,3’,4’,5,7-pentahydroxy-flavone were synthesized and characterized by elemental analysis, molar conductance, IR, 1HNMR, TG-DTA, UV-Vis spectroscopic techniques, and fluorescence analysis. The scavenging effect on the superoxide radical (O2- ) and the inhibitory effect on lipid peroxides were also investigated. Both the ligand and the complexes exhibit scavenging effect on superoxide radicals, and the effect of the complexes is greater than that of the ligand. The Pt(Ⅱ) complex exhibits the strongest scavenging efficiency. Both Pt(Ⅱ) and Pd(Ⅱ) complexes have the inhibitory effect on lipid peroxides, and the effect of the complexes is greater than that of the ligand, but the Pt(Ⅱ) complex has a high effect of promoting lipid peroxides. Pt (Ⅱ) and Pd (Ⅱ) complexes with 2 ’, 3’, 4 ’, 5,7-pentahydroxy-flavone were synthesized and characterized by elemental analysis, molar conductance, IR, 1HNMR, TG-DTA, Techniques, and fluorescence analysis. The scavenging effect on the superoxide radical (O2-) and the inhibitory effect on lipid peroxides were also investigated. Both the ligand and the complexes exhibit scavenging effect on superoxide radicals, and the effect of the complexes is greater than that of the ligand. The Pt (Ⅱ) complex exhibits the strongest scavenging efficiency. Both Pt (Ⅱ) and Pd (Ⅱ) complexes have the inhibitory effect on lipid peroxides, and the effect of the complexes is greater than that of the ligand, but the Pt (Ⅱ) complex has a high effect of promoting lipid peroxides.
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