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为研究超声造影(CEUS)对肝硬化合并小肝癌(SHCC)的早期诊断价值,本研究随机选取肝硬化合并小肝癌患者33例,共计病灶36个。对透明细胞癌病灶的造影显示,其开始增强时间和增强峰值时间均大于中、低、高分化癌,而开始消退时间显著大于中低分化癌,显著低于高分化癌(p<0.05);对小肝癌病灶的造影显示,开始增强时间与增强峰值时间差异不显著(p>0.05),而高分化癌的开始消退时间显著高于中低分化癌(p<0.05);关于超声造影增强模式,病灶在不同分化期呈现出了不同的造影特点。超声造影后,10个病灶较超声造影前诊断评分有所提高,其中5个病灶的诊断评分较超声造影前提高2分。经回顾性分析算得91.67%的病灶检出病情,69.44%的病灶可确诊。结果表明,超声造影对肝硬化合并小肝癌的确诊率较高,本研究为肝硬化合并小肝癌的临床分析提供了诊断依据。
To study the value of CEUS in the early diagnosis of cirrhosis with small hepatocellular carcinoma (SHCC), we randomly selected 33 patients with cirrhosis and small hepatocellular carcinoma for a total of 36 lesions. The appearance of clear cell carcinoma lesions showed that the time of onset of enhancement and peak time of enhancement were higher than that of moderately, moderately, and poorly differentiated carcinoma, but the onset time of remission was significantly higher than that of moderately poorly differentiated carcinoma (p <0.05). The imaging of small hepatocellular carcinoma showed that there was no significant difference between the initial time and the peak time (p> 0.05), while the time to onset of well-differentiated carcinoma was significantly higher than that of moderately-differentiated carcinoma (p <0.05) The lesions showed different characteristics of angiography in different stages of differentiation. After contrast-enhanced ultrasound, the scores of 10 lesions were higher than those before CEUS, and the diagnostic scores of 5 lesions were increased by 2 points before CEUS. After the retrospective analysis, 91.67% of the lesions were detected, and 69.44% of the lesions were diagnosed. The results showed that the diagnosis of cirrhosis with small hepatocellular carcinoma was more confirmed by contrast-enhanced ultrasound. This study provided the basis for the clinical analysis of cirrhosis combined with small hepatocellular carcinoma.