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采用声学定量技术(AQ)检查26名维持性血透(HD)患者血透前后的心脏。由于在按压动静脉瘘管(AVF)前后分别测量了左心功能各参数,故在较短时间内实现了对同一心脏四种不同负荷情况的心功能研究。AQ法实时测定左室舒张末期容积(EDV),是直接观察心脏前负荷的可靠指标。结果一次HD后,EDV、收缩末期容积(ESV)、每搏输出量(SV)、心排血量(CO)、左室径(LVD)都明显降低。高峰充盈率(PFR)和高峰射血率(PER)明显改善,分别由2.44±0.65增至2.77±0.68(P值=0.005)和2.19±0.49增至2.78±0.76(P值=0.000)。这是由于心脏前负荷减少、心肌代谢状况和很多其他因素改善的结果。
Acoustic quantification (AQ) was used to examine the hearts of 26 patients with maintenance hemodialysis (HD) before and after hemodialysis. Since the parameters of left ventricular function were measured before and after the arteriovenous fistula (AVF), respectively, cardiac function in four different loading conditions of the same heart was achieved in a short period of time. AQ method for real-time determination of left ventricular end-diastolic volume (EDV), is a direct indicator of pre-cardiac load. Results EDV, end-systolic volume (ESV), stroke volume (SV), cardiac output (CO), and left ventricular diameter (LVD) were significantly decreased after an HD treatment. PFR and PER improved significantly from 2.44 ± 0.65 to 2.77 ± 0.68 (P = 0.005) and 2.19 ± 0, respectively. 49 to 2.78 ± 0.76 (P = 0.000). This is the result of a reduction in pre-cardiac load, myocardial metabolic status, and many other factors.