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目的 了解我国HIV感染的高发区新疆伊宁市0-7岁儿童HIV感染率及感染途径,为进一步制定儿童感染HIV的干预措施提供依据。方法 采集儿童手指血2滴,现场进行HIV抗体快速检查,对儿童HIV(+)的母亲随访并进行血清学检查。结果 调查693名0-7岁儿童,HIV抗体阳性1人,HIV感染率0.15％,其母血清HIV抗体阳性,通过DNA序列测定,均为HIV-1 C亚型。结论 新疆伊宁市HIV的传播已从高危人群波及一般人群,并出现母婴传播,应采取有力的措施控制HIV传播。
Objective To understand the prevalence of HIV infection and the route of infection among children aged 0-7 years in Yining, Xinjiang, a high prevalence area of HIV infection in our country and provide the basis for further developing interventions for children infected with HIV. Methods Two finger blood samples were collected from children and HIV antibody was detected on site. The mothers of children with HIV (+) were followed up and serologically investigated. Results A total of 693 children aged 0-7 years were tested for HIV-1 C subtype 1 HIV-1 positive and HIV-1 infection rate 0.15%. Their maternal serum HIV antibodies were positive by DNA sequencing. Conclusion HIV transmission in Yining, Xinjiang has spread from the high-risk groups to the general population, and there is mother-to-child transmission. Therefore, effective measures should be taken to control the spread of HIV.