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患者,男,53岁,以多饮,多尿,消瘦8年,反复口腔、外生殖器溃疡4年入院.1982年开始出现烦渴多饮,小便次数增多,尿量每天达约3500ml,大便清稀,每天1～2次,日渐消瘦.查血糖10.5mmol/L.给予低糖饮食,口服D_(860),间断皮下注射胰岛素.1986年反复出现口腔粘膜及外生殖器溃疡,其症状和血糖的高低有关.血糖升高则出现溃疡,血糖控制后溃疡逐渐愈合,口服Vit+B_2无效.查体:T36.5C,P70次/分,R18次/分.BP18.6/12kPa,发育营养正常,消瘦,体重48kg,皮肤干燥.双前背静脉穿刺针孔处均有小脓疮,眼睑无充血水肿,视力正常,口角及香系带处可见0.4×0.4cm大小的白色溃疡.心肺(一).肝脾肋下未触及,右小腿及足背部触及多个结节红斑.触痛明显,阴囊及阴茎冠状沟处可见多处白色溃疡.范围均在0.5×0.5cm左右.足背动脉搏动正常.实验室检查:空腹血糖10.8mmol/L,
Patients, male, 53 years old, with polydipsia, polyuria, weight loss for 8 years, repeated oral and external genital ulcer 4 years admitted to .1982 began to appear polydipsia, diuretic times increased, urine output of about 3500ml per day, stool clear Dilute, 1 or 2 times a day, getting thinner.Check blood sugar 10.5mmol / L. Give a low-sugar diet, oral D_ (860), intermittent subcutaneous injection of insulin .1986 repeated oral mucosa and genital ulcers, the symptoms and the level of blood sugar Related to the rise in blood sugar, ulcers, ulcers gradually healed after glycemic control, oral Vit + B_2 invalid. Physical examination: T36.5C, P70 beats / min, R18 beats / min .BP18.6 / 12kPa, normal nutrition, weight loss , Weight 48kg, dry skin.Double anterior descending venous puncture are small abscess, edema edema eyelid, normal eyesight, mouth and the Department of incense with visible 0.4 × 0.4cm white ulcer size. Not touching the liver and spleen ribs, right leg and foot dorsal touch multiple nodules erythema.Cutal tenderness, scrotum and penile coronary canal at many white ulcers can be found in the range of 0.5 × 0.5cm around the dorsalis pedis artery pulsation normal. Laboratory tests: fasting blood glucose 10.8mmol / L,