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为了解吸附精制白喉破伤风Ｍ联类毒素（ＤＴ）减量（０．２ｍｌ）加强免疫后的效果，１９９７年１月和３月，在上默特左旗察素齐镇第七小学，用北京生物制品研究所生产的ＵＴ，给１５４名７岁小学生每人注射０．２ｍｌ。结果无一人发热或发生接种部位红肿等临床反应，检测其中５３份免疫前和后配对的血清，免疫前白喉抗毒素阳性率为８６．７９％，免疫后达１００％；免疫后有％．２３％的儿童抗体滴度有４倍以上增长．同样，检测５０份免疫前后配对的血清，免疫前破伤风抗毒素阳性率为８８．００％，免疫后达１００％；免疫后有９６．００％的儿童抗体滴度有４倍以上增长．这说明减量加强免疫是安全的，近期免疫效果是满意的，但其免疫持久性需进一步观察。
In order to understand the effect of decontamination, diphtheria and tetanus M-tetanus toxoid (DT) dose reduction (0.2 ml) to enhance the post-immune effect, in January and March 1997, Beijing Institute of Biological Products UT, to 154 seven-year-old primary school injection of 0.2ml per person. Results No one had fever or swollen inoculation site and other clinical reactions. Among them, 53 were tested before and after immunization. The positive rate of antitoxin before diphtheria was 86.79% and 100% after immunization; Twenty-three percent of children had more than 4 times more titers. Similarly, 50 pairs of pre-immune and post-immunized paired sera were detected. The positive rate of tetanus antitoxin before immunization was 88.00% and 100% after immunization. The antibody titer in 96.00% of immunized children increased more than 4 times after immunization. This shows that reduced-dose immunization is safe, the recent immunization is satisfactory, but its immune persistence needs further observation.