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研究葛根素治疗短暂性脑缺血患者的作用。方法:选取2012年7月至2015年6月收治的脑缺血患者128例,随机分为治疗组62例和对照组66例。对照组患者给予抗血小板聚集、低温及脑保护剂保护脑细胞等治疗,治疗组在对照组基础上静脉滴注葛根素注射液,两组均连续治疗2周。比较两组临床疗效,观察患者脑缺血发作次数、发作停止时间及治疗期间不良反应。结果:治疗组总有效率明显优于对照组,差异具有统计学意义;治疗组脑缺血发作次数明显少于对照组,发作停止时间明显短于对照组,差异具有统计学意义(P<0.01);不良反应比较轻微,不影响治疗。两组不良反应比较差异无统计学意义(P>0.05)。结论:葛根素治疗脑缺血疗效较好,可减少脑缺血发作次数,缩短发作时间,且安全性比较高,值得临床推广。
To study the effect of puerarin on patients with transient cerebral ischemia. Methods: A total of 128 patients with cerebral ischemia admitted from July 2012 to June 2015 were randomly divided into treatment group (n = 62) and control group (n = 66). Patients in the control group were given antiplatelet aggregation, hypothermia and brain protective agent to protect brain cells. The treatment group was given puerarin on the basis of the control group, and both groups were treated continuously for 2 weeks. The clinical efficacy was compared between the two groups. The number of ischemic attacks, the stopping time and the adverse reactions during the treatment were observed. Results: The total effective rate of the treatment group was significantly better than that of the control group, the difference was statistically significant; the number of ischemic attacks in the treatment group was significantly less than that of the control group, the stopping time was significantly shorter than the control group, the difference was statistically significant (P <0.01 ); Adverse reactions are mild, does not affect the treatment. There was no significant difference in adverse reactions between the two groups (P> 0.05). Conclusion: Puerarin treatment of cerebral ischemia better curative effect, can reduce the number of ischemic attacks, shorten the attack time, and the safety is relatively high, worthy of clinical promotion.