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为分析白血病自发性颅内出血的特点,对35例因白血病死亡者进行颅脑解剖,作大体与显微镜下观察。结果表明,并发颅内出血者24例,占68.6%。因颅内出血发生脑疝致死者16例,占45.7%。出血病灶部位发生频率分布最高的是脑膜(17例,占70.8%),66.7%的出血病灶位于2个或更多个部位。瘤细胞颅内浸润25例中,并发颅内出血者23例,占92%(P<0.05)。结论:颅内出血是白血病预后不良的重要指标,其特点是出血部位表浅,病变呈多灶性,其原因是出血部位瘤细胞的浸润。
In order to analyze the characteristics of spontaneous intracranial hemorrhage of leukemia, 35 cases of cranial cerebral hemorrhage due to leukemia were dissected for general and microscopic observation. The results showed that 24 cases of intracranial hemorrhage, accounting for 68.6%. Due to intracranial hemorrhage occurred in 16 cases of brain hernia, accounting for 45.7%. The most frequent sites of hemorrhagic lesions were the meninges (17 cases, 70.8%), and 66.7% of the hemorrhagic lesions were located in 2 or more sites. Tumor cells in 25 cases of intracranial infiltration, intracranial hemorrhage in 23 cases, accounting for 92% (P <0.05). Conclusion: Intracranial hemorrhage is an important indicator of poor prognosis of leukemia, which is characterized by superficial bleeding, lesions were multifocal, the reason is that the bleeding site of tumor infiltration.