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1.结核菌素试验阳性是否表明体内有活结核杆菌存在? 一般认为结核菌素试验阳性者体内有分枝杆菌存在。与结核杆菌抗原性有关的分枝杆菌可引起弱阳性反应,但强阳性者通常表明有活结核杆菌存在。大量实验和流行病学证据表明阳性皮肤试验与话菌存在相关。注射死结核菌的动物结核菌素反应阳性仅持续很短时间,而结核菌苗接种者,反应阳性可持续3～4年以上。感染结核杆菌的动物的阳性反应经化疗后转阴。结核菌素试验阳性儿童,经一个疗程异烟肼治疗后转阴。不过,结核菌素致敏的人或动物,反复注射结核菌素可使反应加强,或使反应转阳。结核菌素试验一度阳性,后因细菌死亡或化疗杀菌后阴转者,经数日或数周进行结核菌素试验可恢复阳性反应。这种回忆反应(常称为威利斯现象),是暂时的,很快消失。 2.结核菌苗对结核病的预防价值?
1. tuberculin test positive whether the presence of live TB in the body? Generally considered tuberculin test positive for the presence of mycobacteria. Mycobacteria associated with Mycobacterium tuberculosis antigenicity can cause a weak positive reaction, but strong positives usually indicate the presence of Mycobacterium tuberculosis. Numerous experimental and epidemiological evidences indicate that positive skin tests are associated with the presence of bacteria. Tuberculin injection dead M. tuberculosis animals positive only for a very short period of time, and vaccination of tuberculosis vaccine, the reaction can last 3 to 4 years. The positive reaction in animals infected with Mycobacterium tuberculosis turned negative after chemotherapy. Tuberculin test positive children, after a course of treatment isoniazid negative. However, tuberculin-sensitized people or animals, repeated injection of tuberculin can make the reaction to strengthen, or the reaction yang. Once positive tuberculin test, after the death of the bacteria or chemotherapy after sterilization of negative conversion, after several days or weeks of tuberculin test can be restored positive reaction. This recall reaction (often called the Willis phenomenon) is temporary and disappears quickly. 2. tuberculosis vaccine prevention of tuberculosis value?