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为确定儿童尖锐湿疣的致病人乳头状瘤病毒(HPV)类型及传播方式,作者研究了32名患肛门生殖器疣儿童(其中男11例、女21例),其年龄分布于产后10个月至11岁,平均为5岁3个月。同时对其30名母亲及28名父亲进行检查,发现12名患儿母亲及10名患儿父亲患有外生型疣,10名患儿母亲(其中2名无外生型疣)患有宫颈扁平湿疣。应用印迹杂交法(Blot Hybridization)研究27名患儿肛门生殖器疣标本,24例检出HPV,其中HPV-6型13例,HPV-11型2例,HPV-2型7例,有2例小儿生殖器疣标本中检出目前尚未分类的HPV-DNA;从12例患儿母亲的生殖器疣及手寻常疣标本中共检出HPV7例,其中HPV-6型5
To determine the type and transmission of HPV in children with condyloma acuminatum, the authors studied 32 children with genital warts (11 males and 21 females) aged 10 months postpartum To 11 years old, with an average of 5 years and 3 months. At the same time, 30 mothers and 28 fathers were examined. Twelve mothers with 10 mothers and 10 mothers with genital warts and 10 mothers (2 of which had no exophytic warts) were found to have cervical Flat condyloma. Twenty-seven cases of anogenital warts were studied by Blot Hybridization and 24 cases were detected HPV, including 13 cases of HPV-6, 2 cases of HPV-11, 7 cases of HPV-2 and 2 cases of pediatric HPV-DNA was detected in genital wart samples, HPV7 was detected in genital warts and verruca vulgaris in 12 mothers, of which HPV-6 type 5