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2型糖尿病患者除了胰岛素的绝对和(或)相对缺乏及胰岛素抵抗外,往往合并其他激素水平的紊乱及活性的改变。骨质疏松是糖尿病的并发症,糖皮质激素可能参与此过程,血糖控制较差的患者,此激素水平较高。性激素与胰岛素抵抗有关,雌激素水平降低与女性绝经后糖尿病的发病率增加有关。瘦素是连接肥胖和2型糖尿病的纽带。糖尿病肾病患者肾素-血管紧张索的活性发生改变。对2型糖尿病与激素的研究将有助于预防糖尿病并发症的发生,从而有效降低病残率和病死率。
In addition to the absolute and / or relative lack of insulin and insulin resistance, patients with type 2 diabetes mellitus often have disorders and changes in activity that are associated with other hormone levels. Osteoporosis is a complication of diabetes. Glucocorticoids may be involved in this process, and patients with poor glycemic control have high levels of this hormone. Sex hormones are associated with insulin resistance, and estrogen levels are associated with an increased incidence of postmenopausal diabetes in women. Leptin is a link between obesity and type 2 diabetes. Renal angiotensin-converting enzyme activity changes in patients with diabetic nephropathy. Research on type 2 diabetes and hormones will help prevent the complications of diabetes and thus reduce morbidity and mortality.