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克矽平简称p204,化学名为:聚2-乙烯吡啶氮氧化物(poIy-2-VinyIpyridine-N-Oxide),国外常缩写为pVNO。 自从1961年SChIpkoeter氏报告了p204对实验性矽肺具有完全性地抑制纤维化作用后,引起了矽肺研究界的重视。我国医药卫生工作者,在毛主席的革命路线指引下,较深入的进行了药理实验研究,于1967年首先过渡到临床试用,至1970年召开了鉴定会议,证明是对实验性矽肺兼具予防和治疗作用,可延缓矽肺病进展,毒性不大的一种药物。根据近十年来国内外实验研究已初步证明具有:(1)抑制纤维化作用;(2)
Silicone referred to as p204, chemical name: poly 2-vinyl pyridine nitrogen oxide (poIy-2-VinyIpyridine-N-Oxide), foreign often abbreviated as pVNO. Since 1961, SChIpkoeter’s report of p204 on experimental silicosis with complete inhibition of fibrosis, has drawn the attention of the silicosis research community. Under the guidance of Chairman Mao’s revolutionary line, Chinese medical and hygienic workers conducted a more in-depth study of pharmacological experiments. They first made a transition to clinical trial in 1967 and an appraisal meeting was held in 1970, proving that they should both guard against experimental silicosis And the role of treatment, can delay the progress of silicosis, toxicity is not a drug. According to the experimental studies at home and abroad in the past decade, it has been initially demonstrated that: (1) inhibition of fibrosis; (2)