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Objective: To study the effect of polysaccharide peptide (PSP) on the reconstruction of the hematopoietic function in mice irradiated by lethal dose. Methods: The characteristics of proliferation of colony forming unit granulocyte macrophage (CFU GM) and colony forming unit spleen (CFU S) were measured after continuous injection of PSP in mice for seven days with different doses. Results: Injection of 25 mg/kg PSP in mice could promote and increase CFU GM proliferation and cell mitosis, markedly enhance survival ratio, survival time and CFU S. Conclusions: PSP has significant regulative effects on the reconstruction of the hematopoietic and the immunologic functions in mice irradiated by lethal dose.
Objective: To study the effect of polysaccharide peptide (PSP) on the reconstruction of the hematopoietic function in mice irradiated by lethal dose. Methods: The characteristics of proliferation of colony forming unit granulocyte macrophage (CFU GM) and colony forming unit spleen Results: Injection of 25 mg / kg PSP could promote and increase CFU GM proliferation and cell mitosis, markedly enhance survival ratio, survival time and CFU S. Conclusions: PSP has significant regulatory effects on the reconstruction of the hematopoietic and the immunologic functions in mice irradiated by lethal dose.