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目的:探讨重症监护病房(ICU)多器官功能障碍综合征(MODS)患者持续性血液净化(CBP)治疗对出血并发症的影响。方法:分析我院ICU CBP治疗存活1周以上的MODS患者48例,根据出血并发症情况分为出血组和无出血组,对其CBP前血小板计数和血凝分析、肝肾功能进行比较。结果:与未出血组比较,出血组凝血功能、血小板计数、肾功能、总胆红素水平均有显著差异。结论:ICU MODS患者病情危重,出血风险大,应密切监测凝血功能及肝肾功能,采用适宜的抗凝方案,减少出血并发症的发生。
Objective: To investigate the effect of continuous blood purification (CBP) on bleeding complications in intensive care unit (ICU) patients with multiple organ dysfunction syndrome (MODS). Methods: Forty-eight patients with MODS survived for more than 1 week in our hospital were divided into hemorrhagic group and non-hemorrhagic group according to the complication of hemorrhage, and their pre-CBP platelet count, hemagglutination and liver-kidney function were compared. Results: Compared with non-hemorrhage group, hemorrhagic coagulation, platelet count, renal function, total bilirubin were significantly different. CONCLUSIONS: Patients in ICU MODS are critically ill and have a high risk of bleeding. Clotting function and liver and renal function should be monitored closely. Appropriate anticoagulant regimen should be used to reduce the occurrence of bleeding complications.