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检验医学院、生命科学学院黄传书教授、高基民教授领衔的肿瘤新靶标的发现及应用团队经过四年多的研究,首次揭示了自噬与炎症的关系及在镍化物致肺癌发生过程中的作用及机制。日前,该团队研究论文《Upregulation of SQSTM1/p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells》在国际知名杂志《Autophagy》(五年平均影响因子11.958)上发表。
After more than four years of research, the team of discovery and application of new tumor targets led by Professor Huang Chuanshu and Professor Gao Jimin from Laboratory Medicine and Life Sciences College revealed for the first time the relationship between autophagy and inflammation and its role in lung carcinogenesis caused by nickel compounds. mechanism. The team’s research paper “Upregulation of SQSTM1 / p62 contributes to nickel-induced malignant transformation of human bronchial epithelial cells” was published in the internationally renowned journal Autophagy (Five-Year Mean Impact Factor 11.958).