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目的:探讨甲巯咪唑治疗糖尿病合并甲状腺功能亢进症的临床效果。方法:2012年8月到2015年2月选择在我院诊治的糖尿病合并甲状腺功能亢进症患者60例,根据入院顺序分为治疗组与对照组各30例,对照组口服丙硫氧嘧啶片,治疗治疗组口服甲巯咪唑片治疗,都治疗1个月。结果:治疗后治疗组与对照组的有效率分别为96.7%和86.7%,治疗组的有效率明显高于对照组(P<0.05)。两组治疗后的游离甲状腺激素含量都明显低于治疗前(P<0.05),同时治疗后治疗组的游离甲状腺激素含量明显低于对照组(P<0.05)。结论:甲巯咪唑治疗糖尿病合并甲状腺功能亢进症能有效促进游离甲状腺激素分泌正常,从而提高治疗疗效,有很好的应用价值。
Objective: To investigate the clinical effect of methimazole in the treatment of diabetic patients complicated with hyperthyroidism. Methods: From August 2012 to February 2015, 60 patients with diabetes mellitus complicated with hyperthyroidism who were diagnosed and treated in our hospital were divided into treatment group (30 cases) and control group (30 cases). The control group was given propylthiouracil tablets Treatment treatment group oral methimazole tablets treatment, are treated for 1 month. Results: After treatment, the effective rates of the treatment group and the control group were 96.7% and 86.7%, respectively. The effective rate of the treatment group was significantly higher than that of the control group (P <0.05). Free thyroid hormone levels in both groups were significantly lower than those before treatment (P <0.05). After treatment, the free thyroid hormone levels in the treatment group were significantly lower than those in the control group (P <0.05). Conclusion: Methimazole treatment of diabetic patients with hyperthyroidism can effectively promote the secretion of free thyroid hormones, thereby enhancing the therapeutic effect, have good value.