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世界上有三分之一的人口被结核病分枝杆菌(Mtb)感染,但只有其中5%~10%的被感染个体在他们一生中发展为活动性肺结核(TB),剩余的90%~95%个体保持健康并被称为潜在感染个体。他们是结核杆菌最大的载体,并且确定潜在的肺结核案例是全球控制肺结核计划的一部分。从临床观点发现最高活动性肺结核风险的潜在性结核感染个体包含人体免疫缺陷病毒(HIV)感染、自身免疫感染性疾病或癌症案例。本文总结了潜在性肺结核的发病机制、它的诊断、治疗和预防等的最新研究进展。
One third of the world’s population is infected with Mtb, but only 5% to 10% of infected individuals develop active tuberculosis (TB) throughout their lifetime, with the remaining 90% to 95% % Of individuals stay healthy and are referred to as potentially infected individuals. They are the largest carriers of Mycobacterium tuberculosis, and identifying potential cases of tuberculosis is part of a global control of tuberculosis program. Potential TB Infections Identifying the Most Active Pulmonary Tuberculosis Risk from a Clinical Perspective The individual contains a human immunodeficiency virus (HIV) infection, an autoimmune infectious disease, or a cancer case. This article summarizes the pathogenesis of potential pulmonary tuberculosis, its diagnosis, treatment and prevention of the latest research progress.