^99mTc-YIGSR as a Receptor Tracer in Imaging the Ehrlich Ascites Tumor-bearing Mice as Compared with

• 作 者: 胡佳 秦光明 张永学 安锐 兰小莉
• 机 构: DepartmentofNuclearMedicine,TheKeyLaboratoryofMolecularImagingofHubeiProvince,DepartmentofNuclearMed
• 出 处: 华中科技大学学报：医学英德文版
• 发表日期: 2007年4期
• 关键词: 肿瘤 受体 生物标记 ^99MTC laminin-YIGSR tumor receptor imaging radio-labeling ^99mTC
• 基金项目: This project was supported by a grant from the National Natural Sciences Foundation of China （No. 30400170）.

The validity of 99mTc-YIGSR,a novel receptor radio-tracer,in imaging the Ehrlich ascites tumor was evaluated.YIGSR,a pentapeptide of laminin,was labeled with 99mTc by using a bifunc-tional chelator S-Acetly-NH3-MAG3.The MIBI was labeled with 99mTc by foll