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目的比较奥美拉唑与兰索拉唑治疗老年消化性溃疡的临床疗效。方法选取2013年6月—2015年6月长沙市精神病院收治的老年消化性溃疡患者192例,随机分为观察组与对照组,各96例。对照组患者予以奥美拉唑治疗,观察组患者予以兰索拉唑治疗。观察两组患者临床疗效及不良反应发生情况。结果观察组患者总有效率高于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论兰索拉唑治疗老年消化性溃疡的临床疗效好于奥美拉唑,且不良反应少。
Objective To compare the clinical efficacy of omeprazole and lansoprazole in the treatment of senile peptic ulcer. Methods A total of 192 elderly patients with peptic ulcer admitted to Changsha Mental Hospital from June 2013 to June 2015 were randomly divided into observation group and control group with 96 cases each. Patients in the control group were treated with omeprazole, and patients in the observation group were treated with lansoprazole. The clinical efficacy and adverse reactions of the two groups were observed. Results The total effective rate of observation group was higher than that of control group, the incidence of adverse reactions was lower than that of control group, the difference was statistically significant (P <0.05). Conclusions Lansoprazole is superior to omeprazole in the treatment of senile peptic ulcer with less adverse reactions.