论文部分内容阅读
目的:观察脑心通胶囊对冠心病稳定型心绞痛患者血清超敏C反应蛋白(hs-CRP)、白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)的影响。方法:将101例冠心病稳定型心绞痛患者随机分为两组,对照组予西药治疗,治疗组在此基础上加用脑心通胶囊,治疗前后检测血清hs-CRP、IL-6和TNF-α水平。结果:治疗组显效率及总有效率均显著高于对照组(P<0.05),治疗后血清hs-CRP、IL-6和TNF-α水平亦明显低于对照组(P<0.05)。结论:脑心通胶囊具有下调冠心病稳定型心绞痛患者血清hs-CRP、IL-6和TNF-α水平作用,可能是其发挥治疗作用机制之一。
Objective: To observe the effects of Naoxintong Capsules on serum hs-CRP, IL-6 and TNF-α in patients with coronary heart disease and stable angina pectoris. Methods: 101 patients with stable angina pectoris of coronary heart disease were randomly divided into two groups. The control group was treated with western medicine. On the basis of this, the treatment group was given Naoxintong capsule. Serum hs-CRP, IL-6 and TNF- α level. Results: The effective rate and total effective rate of the treatment group were significantly higher than those of the control group (P <0.05). The levels of serum hs-CRP, IL-6 and TNF-α after treatment were also significantly lower than those of the control group (P <0.05). Conclusion: Naoxintong Capsule has the effect of down-regulating hs-CRP, IL-6 and TNF-α levels in patients with stable angina pectoris of coronary heart disease, which may be one of the mechanisms of its action.