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本文作者报道4例儿童急性巨核细胞白血病(AMKL),并对其病程与先前报道的16例 AMKL进行了比较。20例儿童 AMKL,诊断时年龄5月—14岁,10例年龄小于2岁,9男11女。进行了活检的病人均有骨髓纤维化,12例白细胞计数小于10×10~3/1,4例外周血中白血病细胞大于10×10~9/1。19例中12例器官肿大,主要在年幼病儿,4例少年病人白细胞计数正常或低于正常。没有器官肿大。作者报道的4例病人,2例最初诊断为低危组儿
The authors report four cases of childhood acute myeloid leukemia (AMKL), and the course of its previous reports of 16 cases of AMKL were compared. 20 cases of children with AMKL, age at diagnosis of May -14 years old, 10 cases of younger than 2 years old, 9 males and 11 females. All patients undergoing biopsy had myelofibrosis with 12 white blood cell counts of less than 10 × 10-3 / 1 of peripheral blood leukemia cells larger than 10 × 10 ~ 9 / 1. Among the 19 patients, 12 had enlarged organs, mainly In young children, 4 cases of juvenile patients with normal or lower than normal white blood cell count. No organ enlargement. The authors reported 4 patients, 2 initially diagnosed as low-risk children