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临床实践表明,大剂量肝素对不稳定型心绞痛(UAP)有效。能使心肌梗死发生率和死亡率下降2~7倍。肝素按分子量(2000~80000)大小分为不同类型:分子量小于5000为低分子肝素,抗Xa因子活性很强,抗凝血酶活性很弱,而分子量大于20000为高分子肝素,抗Xa因子活性很弱,抗凝血酶活性很强。近年为防治静脉血栓已广泛应用低分
Clinical practice shows that high-dose heparin is effective for unstable angina (UAP). Can reduce the incidence of myocardial infarction and mortality 2 to 7 times. According to the molecular weight (2000 ~ 80000), heparin is divided into different types: molecular weight less than 5000 for low molecular weight heparin, strong anti-factor Xa activity, antithrombin activity is very weak, and molecular weight greater than 20,000 for the high molecular weight heparin, anti-factor Xa activity Very weak, strong antithrombin activity. In recent years, prevention and treatment of venous thrombosis has been widely used low score