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目的:探讨数字减影血管造影(DSA)及超声造影(CEUS)评估颅外段颈动脉狭窄检出率及病变程度的价值。方法:运用常规超声和CEUS对颅外段颈动脉狭窄患者进行显像,判断狭窄的部位及程度,与DSA结果相对比。结果:本组患者经DSA及CEUS检查后发现,CEUS较常规超声明显改善了对血管狭窄的检出,以DSA结果为金标准,常规超声和CEUS对轻中度狭窄、重度狭窄、完全闭塞的判断符合率分别为74.8%和90.3%(P<0.05)、63.5%和96.2%(P<0.01)、35.7%和100%(P<0.05)。CEUS和DSA对狭窄率计算值呈显著线性正相关(r=0.929,P<0.001)。结论:CEUS优于常规超声,与DSA相关性较高,能够较为准确、无创的评估颅外段颈动脉狭窄。
Objective: To evaluate the value of digital subtraction angiography (DSA) and contrast-enhanced ultrasound (CEUS) in assessing the detection rate and severity of extracranial carotid artery stenosis. Methods: The extracranial carotid stenosis patients were visualized by conventional ultrasound and CEUS to determine the location and extent of stenosis, as compared with DSA results. Results: The results of DSA and CEUS showed that CEUS significantly improved the detection of vascular stenosis compared with conventional ultrasound. The DSA results were the gold standard. Conventional ultrasonography and CEUS were effective in treating mild to moderate stenosis, severe stenosis and complete occlusion The coincidence rates were 74.8% and 90.3% (P <0.05), 63.5% and 96.2% (P <0.01), 35.7% and 100% respectively (P <0.05). There was a significant linear positive correlation between CEUS and DSA (r = 0.929, P <0.001). CONCLUSIONS: CEUS is superior to conventional ultrasound and has a high correlation with DSA. It can accurately and noninvasively evaluate extracranial carotid stenosis.