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目的：探究氧氟沙星滴耳液在急性化脓性中耳炎治疗中的临床应用。方法80例急性化脓性中耳炎患儿,按照治疗方法分为对照组和治疗组,各40例。对照组采用氯霉素滴耳液进行治疗,治疗组采用氧氟沙星滴耳液进行治疗。比较两组治疗后的效果、听力改善情况、药物起效时间及药物不良反应发生率。结果治疗后,治疗组治疗总有效率82.50%高于对照组62.50%,差异具有统计学意义(P<0.05)。治疗组患儿的听力改善(7.86±2.29)dB、药物起效时间(5.89±1.09)d优于对照组的(3.13±0.76)dB、(9.84±2.23)d,差异均具有统计学意义(P<0.05)。治疗组患儿的药物不良反应发生率5.0%低于对照组20.0%,差异具有统计学意义(P<0.05)。结论采用氧氟沙星滴耳液治疗急性化脓性中耳炎患儿具有较好的疗效,对该病患儿的治疗具有较大的意义,值得推广。“,”ObjectiveTo investigate clinical application of ofloxacin ear drops in the treatment of acute suppurative otitis media.MethodsA total of 80 children patients with acute suppurative otitis media were divided by their treatment measures into control group and treatment group, with 40 cases in each group. The control group received chloramphenicol ear drops for treatment, and the treatment group received ofloxacin ear drops instead. Comparison was made on effects after treatment, hearing improvement, drug effect time, and incidence of adverse drug reactions between the two groups.ResultsAfter treatment, the treatment group had higher total effective rate as 82.50% than 62.50% in the control group, and the difference had statistical significance (P<0.05). The treatment group had all better hearing improvement as (7.86±2.29) dB and drug effect time as (5.89±1.09) d than (3.13±0.76) dB and (9.84±2.23) d in the control group, and their differences all had statistical significance (P<0.05). The treatment group had lower incidence of adverse drug reactions as 5.0% than 20.0% in the control group, and the difference had statistical significance (P<0.05).ConclusionImplement of ofloxacin ear drops shows excellent curative effect in treating acute suppurative otitis media, and it contains important significance for treatment. This method is worth promoting.