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[目的]探讨阴道残端结节细针吸取细胞学检查(fine needle aspiration cytology,FNAC)的临床应用价值。[方法 ]选取115例阴道残端结节患者,随机分成两组,试验组68例阴道残端结节采用FNAC检查;对照组47例采用传统液基细胞学检查,两组患者均进行组织学结果对比研究,分析细胞形态特点与鉴别诊断,比较两种方法诊断的敏感性、特异性和符合率,并分析结节大小、肿瘤分期、首次根治及放化疗至复发的间隔时间与阳性率的关系。[结果]阴道残端结节FNAC检查作为阴道残端肿瘤复发诊断方法的敏感性为90.1%,符合率为92.6%,假阴性率9.8%,假阳性率为0,其中敏感性和假阴性结果显著优于传统液基细胞学方法(P<0.05)。[结论]阴道残端结节FNAC检查可以准确、微创地对阴道残端结节性质进行病理学诊断,具有较高的临床应用价值。
[Objective] To investigate the clinical value of fine needle aspiration cytology (FNAC) in vaginal stump. [Methods] A total of 115 patients with vaginal stump nodules were selected and randomly divided into two groups. 68 cases of vaginal stump nodules in the test group were examined by FNAC. In the control group, 47 patients were treated with traditional liquid-based cytology. Histology The results of comparative study, analysis of cell morphology and differential diagnosis, the sensitivity of the two methods of diagnosis, specificity and compliance rate, and analysis of nodule size, tumor staging, the first radical and radiotherapy and chemotherapy to recurrence interval and the positive rate relationship. [Results] The sensitivity of the vaginal stump nodules FNAC as a diagnostic method of recurrent vaginal stump tumor was 90.1%, the coincidence rate was 92.6%, the false negative rate was 9.8%, the false positive rate was 0, and the sensitivity and false negative results Significantly better than traditional liquid-based cytology (P <0.05). [Conclusion] FNAC examination of vaginal stump nodules can accurately and minimally diagnose the pathological features of vaginal stump nodules, which has a high clinical value.