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在毛细血管水平上,通过对皮肤微循环的直接造影可以了解组织灌注的质量。直角偏振光谱成像(OPS)可以非侵入性地直接观察这些血管。在输血(Tx)之前和输血后2 h和24 h,OPS被用于对13名早产贫血婴儿的上胳膊检查,[(95%CI)中位胎龄:26周(25-26 周),中位出生体重:730 g(652-789 g)]。皮肤灌注的OPS图像能够连续记录下来。通过测量功能性毛细血管密度、血管直径、红细胞速率以及血流,能够得到非线形的毛细血管灌注数量资料。笔者发现,输血2 h后功能性毛细血管密度显著增加,输血24 h之后上升幅度更大[输血前为:142(134-155)cm/cm2,2 h之后为:185 (166-196)cm/cm2,24 h之后为:206(185-219) cm/cm2,P<0.001],因此表明毛细血管灌注改善了,而血管直径、红细胞生成速率以及血流量并没有明显的改变。临床变量如血压、心率、体温也没有显著改
At the level of capillaries, the quality of tissue perfusion can be understood by direct imaging of the microcirculation of the skin. Right-angle polarized spectral imaging (OPS) allows direct observation of these vessels non-invasively. OPS was used for upper arm examinations of 13 premature anemic infants before transfusion (Tx) and 2 h and 24 h after transfusion [median (95% CI) gestational age: 26 weeks (25-26 weeks) Median birth weight: 730 g (652-789 g)]. Skin perfusion OPS images can be continuously recorded. By measuring functional capillary density, vessel diameter, erythrocyte rate, and blood flow, non-linear capillary perfusion data can be obtained. The authors found that functional capillary density increased significantly after 2 h of transfusion, with a greater increase after 24 h of transfusion (142 (134-155) cm / cm2 before transfusion, 185 (166-196) cm / cm2 for 24 h followed by 206 (185-219) cm / cm2, P <0.001], indicating improved capillary perfusion with no significant changes in vessel diameter, erythropoietic rate, and blood flow. Clinical variables such as blood pressure, heart rate, body temperature did not change significantly