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目的:观察米非司酮配米索前列醇终止10~16周妊娠流产的疗效。方法:对妊娠10~16周要终止的的186例妇女给予米非司酮服用50mg,12小时1次,连服2天,总量200mg,第3天晨8加服米索前列醇600ug,用药4小时后无宫缩予米索前列醇400ug置阴道后穹窿。结果:完全流产114例,占61.28%;不完全流产55例,占30.14%;失败17例占8.58%,有效率91.42%。结论:大剂量米非司酮配米索前列醇终止10~16周妊娠成功率高、副作用小,是一种安全、方便、较为有效的方法。
Objective: To observe the curative effect of mifepristone with misoprostol to terminate the abortion of 10 ~ 16 weeks. Methods: To terminate the pregnancy of 10 to 16 weeks of 186 women given mifepristone take 50mg, 12 hours 1, and even for 2 days, the total 200mg, the morning of the 3rd day 8 plus misoprostol 600ug, 4 hours after treatment without contractions misoprostol 400ug set vaginal fornix. Results: Complete abortion in 114 cases, accounting for 61.28%; 55 cases of incomplete abortion, accounting for 30.14%; failed 17 cases accounted for 8.58%, the effective rate was 91.42%. Conclusion: High-dose mifepristone plus misoprostol is a safe, convenient and effective method to terminate the pregnancy with 10 to 16 weeks of pregnancy with high success rate and small side effects.