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本文报告了9例急性非淋巴细胞性白血病(ANLL)病人的临床、形态学特征及少见的易位t(6;9)(p23;q34).病例中,男4例,女5例;年龄5～51岁,年龄中位数为38岁,较在一般ANLL所见要低.按FAB标准分类:M_11例,M_24例,M_43例,1例由RAEB演化为M_2型.对治疗前的骨髓Romanowsky染色标本进行分析,每标本分类计数500～2,000个细胞.对照组骨髓标本至少计数400个细胞.全部结果由有经验的技师或内科医生审查,嗜碱细胞≥0.25%或无嗜碱细胞的病例均重新计数.染色体分析用胰酶-Giemsa或喹吖因荧光显带技术.
In this paper, we report the clinical and morphological features of 9 patients with acute non-lymphocytic leukemia (ANLL) and their rare translocation t (6; 9) (p23; q34), including 4 males and 5 females, 5 to 51 years old, the median age was 38 years old, lower than that seen in the general ANLL.According to FAB standard classification: M_11 cases, M_24 cases, M_43 cases, 1 case of RAEB evolved into M_2 type.Before treatment, Romanowsky stained specimens from 500 to 2,000 cells per specimen and at least 400 cells from the control bone marrow specimens.All the results were reviewed by an experienced technician or physician with> 0.25% basophils or basophils All cases were recalculated.Chromosome analysis using trypsin-Giemsa or quinacrine fluorescence banding technique.