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我们对久居高原现返回平原定居的63例中、老年人和快速进入平原的45例健康人及9例高原红细胞增多症患者进行了红细胞——超氧化物歧化酶(RBC—SOD)的测定。结果表明:①久居高原(平均19年)的中、老年人返回平原定居后,RBC—SOD的水平明显高于高原居民(P<0.01),但仍低于平原同龄人水平(P<0.01)。②高原健康人和高原红细胞增多症患者进入平原7—10天内,RBC—SOD水平明显升高。前者由1350±133u/gHb升至1480±138u/gHb(P<0.01),后者由966±115u/gHb升至1120±133u/gHb(P<0.01)。文章对高原人进入平原后RBC—SOD升高的原因和意义进行了初步探讨。
We measured the erythrocyte superoxide dismutase (RBC-SOD) in 63 elderly people, 45 healthy people who entered the plain quickly, and 9 patients with high altitude polycythemia. The results showed that: (1) RBC-SOD was significantly higher (P <0.01), but still lower than that of peers in the same age group (P <0.01) . ② In plateau healthy people and patients with high altitude polycythemia, the levels of RBC-SOD were significantly increased within 7-10 days after entering the plain. The former increased from 1350 ± 133u / gHb to 1480 ± 138u / gHb (P <0.01), while the latter increased from 966 ± 115u / gHb to 1120 ± 133u / gHb (P <0.01). The article made a preliminary discussion on the causes and significance of RBC-SOD rising after plateau people entered the plain.