【摘 要】
：
目的 分析后程加速超分割放射治疗加化疗治疗食管癌的疗效.方法 将75例胸段食管癌患者随机分成2组:常规分割加化疗(CF+C)组:5次/周,2.0 Gy/次,总量DT 66 Gy.放疗期间,加5-氟尿嘧啶(5-Fu)500 mg和顺铂(DDP)20mg静脉滴注,每周1次,共5个周期.后程加速超分割加化疗(LCAF+C)组:常规分割照射30 Gy后,改为2次/d,1.5 Gy/次,间隔≥6 h,追量至
【机 构】
：
032000,山西省介休铁路医院放疗科,032000,山西省介休铁路医院放疗科,山西省肿瘤医院放胸科,山西省肿瘤医院放胸科
论文部分内容阅读
目的 分析后程加速超分割放射治疗加化疗治疗食管癌的疗效.方法 将75例胸段食管癌患者随机分成2组:常规分割加化疗(CF+C)组:5次/周,2.0 Gy/次,总量DT 66 Gy.放疗期间,加5-氟尿嘧啶(5-Fu)500 mg和顺铂(DDP)20mg静脉滴注,每周1次,共5个周期.后程加速超分割加化疗(LCAF+C)组:常规分割照射30 Gy后,改为2次/d,1.5 Gy/次,间隔≥6 h,追量至DT66 Gy.放疗期间,化疗方案同CF+C组.结果 CF+C组和LCAF+C组1,2,3,4年局部控制率分别为52.6%,31.6%,24.7%,23.7%和73.0%,64.9%,59.5%,54.1%(P＜0.01).两组1,2,3,4年生存率分别为52.6%,28.9%,18.4%,15.8%和81.0%,62.2%,51.4%,40.5%,两组差异均有统计学意义(P＜0.05).但两组的急性血液学毒副反应(如白细胞和血小板减少)和消化道毒副反应较重.LCAF+C组的放射性食管炎和放射性气管炎较CF+C组明显,但差异无统计学意义,经对症处理后均能耐受.结论 后程加速超分割放射治疗能明显提高食管癌的局部控制率和生存率,但同期化疗能否降低远处转移率有待进一步研究。
其他文献
The various types of granite landforms in the Huangshan Mt. are distributed in a concentric pattern. The remaining parts of the planation surface are in the cen
Since ancient times, the Chinese government has always attached a great deal of importance to food security . However, the problems have been different at diffe
手术在希腊文中的解释:用手工作之意——既以手工操作为主的医疗技术。医疗器械的进步是手术发展的重要推动力,可以说没有医疗器械的进步就没有现代外科。在直肠癌手术中,吻
本文通过对公用事业价格规制中存在问题的分析,提出进一步完善公用事业价格规制的思路,即在价格主管部门主导下,公用事业企业、消费者等相互制约、相互协调、公开透明,共同参
AIM: To investigate whether alphastatin could inhibit human gastric cancer growth and furthermore whether sphingosine kinase (SPK) activity is involved in this
An approach of separating individual wave arrivals for a dipole logging is presented. The branch points are treated as a type of logarithm and the Riemann surfa
Background. Adenoid cystic carcinoma of the cervix is a rare and aggressive neoplasm for which there are no standardized treatment protocols. Case. A 38-year-ol
近日,山西华圆90万t/a煤层气经甲醇制二甲醚项目在寿阳县举行奠基仪式。本项目总投资53亿元,是目前亚洲最大的煤层气开发利用项目。煤层气作为煤矿开采的有害气体直接排入大
请下载后查看，本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.
AIM: To study the expression of vascular endothelial growth factor A (VEGF-A) and VEGF-C and to determine whether the presence of VEGF-A and VEGF-C was associat