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目的探讨小儿过敏性紫癜肾炎的临床特点及其肝素的临床治疗效果。方法将59例过敏性紫癜肾炎患儿随机分为低分子肝素治疗组32例和常规治疗对照组27例,比较两组的临床疗效。结果对照组和治疗组的临床总有效率分别为70.37%(19/27)和87.50%(28/32),两组总有效率比较,差异有统计学意义(P<0.05)。结论低分子肝素对小儿过敏性紫癜肾炎疗效明显,安全可靠。
Objective To investigate the clinical features of children with Henoch-Schonlein purpura nephritis and the therapeutic effect of heparin on it. Methods Fifty-nine children with allergic purpura nephritis were randomly divided into low molecular weight heparin treatment group (n = 32) and conventional treatment control group (n = 27). The clinical efficacy of the two groups were compared. Results The total effective rates of the control group and the treatment group were 70.37% (19/27) and 87.50% (28/32), respectively. The total effective rate of the two groups was statistically significant (P <0.05). Conclusion Low molecular weight heparin has obvious curative effect on allergic purpura nephritis in children and is safe and reliable.