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目的观察血塞通片联合光凝术治疗糖尿病视网膜病变的临床疗效。方法将153例(265只眼)糖尿病视网膜病变患者随机分为对照组(76例,132只眼)和观察组(77例,133只眼)。两组均采用激光光凝术治疗,观察组同时加服血塞通片。两组疗程均为1个月,观察视力、眼底以及视网膜中央血管动脉参数变化情况。结果观察组视力及眼底总有效率分别为95.5%、94.0%,对照组分别为84.1%、83.3%,观察组视力疗效和眼底疗效均明显优于对照组(P<0.05)。与本组治疗前比较,观察组视网膜中央血管动脉收缩期峰值流速、舒张末期流速、搏动指数均有明显改善(P<0.05),对照组各指标治疗前后差异无统计学意义(P>0.05);组间治疗后比较,收缩期峰值流速、舒张末期流速指标差异有统计学意义(P<0.05)。结论血塞通片联合光凝术治疗糖尿病视网膜病变疗效确切。
Objective To observe the clinical efficacy of Xuesaitong combined with photocoagulation in the treatment of diabetic retinopathy. Methods 153 patients (265 eyes) with diabetic retinopathy were randomly divided into control group (76 eyes, 132 eyes) and observation group (77 eyes, 133 eyes). Both groups were treated with laser photocoagulation, while the observation group plus Xuesaitong tablets. The two courses of treatment were 1 month, visual acuity, fundus and central retinal artery parameters changes. Results The total visual acuity and total fundus fundus in the observation group were 95.5% and 94.0%, respectively, while those in the control group were 84.1% and 83.3% respectively. The visual acuity and ocular fundus in the observation group were significantly better than those in the control group (P <0.05). Compared with before treatment in this group, the peak velocity, end-diastolic velocity and pulsatility index of the central retinal artery were significantly improved in the observation group (P <0.05), but there was no significant difference between the control group before and after treatment (P> 0.05) After treatment, the peak systolic velocity and end-diastolic velocity showed significant difference (P <0.05). Conclusion Xuesaitong combined photocoagulation for the treatment of diabetic retinopathy curative effect.